Opportunity Information: Apply for DFOP0017240
The grant opportunity "Addressing Development and Use of Chemical and Biological Weapons by Russia" (Funding Opportunity Number DFOP0017240) is a discretionary U.S. government program run by the Department of State, Bureau of International Security and Nonproliferation (ISN), under its Cooperative Threat Reduction (CTR) efforts. It is structured as a cooperative agreement, which typically means the government expects substantial involvement in shaping, coordinating, and overseeing the work as it is carried out. The overall purpose is to reduce the national security risks associated with chemical and biological weapons by preventing Russian acquisition of sensitive materials and equipment, and by improving the ability of partners to respond to, investigate, and technically confirm suspected CBW incidents.
The program focuses on three connected lines of effort. First, it aims to work directly with the biological, biotechnology, chemical, and pharmaceutical (BBCP) industry to strengthen compliance and due diligence practices. In practical terms, this means helping companies and supply-chain actors recognize and block procurement attempts that could support CBW development, improving screening of customers and end users, tightening controls over dual-use materials and equipment, and promoting best practices that reduce diversion risk across manufacturing and distribution networks. This component is about prevention: making it harder for Russia to source the inputs needed for CBW-related research, development, production, or weaponization.
Second, the opportunity emphasizes readiness and response in the event of chemical or biological weapons use. ISN/CTR intends to train first responders to assess and secure contaminated sites, manage hazards safely, and collect and transport samples in a way that preserves evidentiary value. A major theme here is maintaining a proper chain of custody from the point of collection through delivery to a detection laboratory, which is essential for credible attribution, legal processes, and international accountability. The goal is to ensure that response actions support both public safety needs and the integrity of subsequent laboratory analysis.
Third, the program supports technical capability building in laboratories, paired with cybersecurity improvements that protect sensitive detection work. Laboratory staff would be trained in CBW detection methods so that beneficiary labs can reliably identify relevant agents and indicators of use. Alongside that technical training, the program plans cybersecurity assessments and select upgrades to protect detection processes, documentation, and reporting systems. This reflects the reality that laboratory results, methods, and reporting chains are high-value targets for interference, manipulation, or theft, and that strong cyber hygiene is part of maintaining confidence in findings.
In terms of funding details, the award ceiling is up to $10,000,000 per award, and the agency anticipates making around 10 awards. The opportunity was created on 2025-05-30, and the original application closing date is 2025-07-30. The listed CFDA number is 19.033, and the funding activity category is labeled "Other," which aligns with its cross-cutting mix of industry engagement, training, laboratory capability, and cybersecurity support rather than a single narrow technical field.
Eligibility is broad and includes U.S. for-profit companies, U.S.-based nonprofits (with or without 501(c)(3) status), and U.S.-based institutions of higher education (public, private, or state). It also allows applications from foreign-based nonprofits/NGOs, Federally Funded Research and Development Centers (FFRDCs), Public International Organizations (PIO), Foreign Public Entities (FPE), and foreign-based institutions of higher education. Overall, the opportunity is designed to bring together operational responders, technical laboratories, cybersecurity expertise, and private-sector supply-chain and compliance capacity to reduce both the likelihood and the impact of CBW development or use tied to Russia.Apply for DFOP0017240
- The Bureau of International Security-Nonproliferation in the other sector is offering a public funding opportunity titled "Addressing Development and Use of Chemical and Biological Weapons by Russia" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 19.033.
- This funding opportunity was created on 2025-05-30.
- Applicants must submit their applications by 2025-07-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $10,000,000.00 in funding.
- The number of recipients for this funding is limited to 10 candidate(s).
- Eligible applicants include: Others.
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Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Addressing Development and Use of Chemical and Biological Weapons by Russia."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is DFOP0017240.
Which U.S. government agency is running this program?
This is a U.S. Department of State program, administered by the Bureau of International Security and Nonproliferation (ISN) under its Cooperative Threat Reduction (CTR) efforts.
Is this a grant or a cooperative agreement?
The award is structured as a cooperative agreement. This typically means the U.S. government expects substantial involvement in shaping, coordinating, and overseeing the work as it is carried out.
What is the overall purpose of this opportunity?
The purpose is to reduce national security risks associated with chemical and biological weapons (CBW) by (1) preventing Russian acquisition of sensitive materials and equipment and (2) improving the ability of partners to respond to, investigate, and technically confirm suspected CBW incidents.
What types of activities does the program support?
The program supports three connected lines of effort: (1) engagement with the biological, biotechnology, chemical, and pharmaceutical (BBCP) industry to strengthen compliance and due diligence, (2) readiness and response training related to CBW use (including evidence-preserving sampling), and (3) laboratory technical capability building for CBW detection paired with cybersecurity improvements that protect sensitive detection work.
What is the first line of effort focused on?
The first line of effort focuses on working with the BBCP industry to strengthen compliance and due diligence practices. This includes helping companies and supply-chain actors recognize and block procurement attempts that could support CBW development, improving screening of customers and end users, tightening controls over dual-use materials and equipment, and promoting best practices that reduce diversion risk across manufacturing and distribution networks.
What does "prevention" mean in the context of this program?
In this program, prevention means making it harder for Russia to source the inputs needed for CBW-related research, development, production, or weaponization by strengthening industry compliance, supply-chain controls, and end-user due diligence.
What is included in the second line of effort (readiness and response)?
The second line of effort emphasizes readiness and response in the event of chemical or biological weapons use. It includes training first responders to assess and secure contaminated sites, manage hazards safely, and collect and transport samples in a way that preserves evidentiary value.
Why is chain of custody emphasized?
Maintaining a proper chain of custody from the point of collection through delivery to a detection laboratory is essential for credible attribution, legal processes, and international accountability. The program aims to ensure response actions support both public safety and the integrity of subsequent laboratory analysis.
What is included in the third line of effort (laboratories and cybersecurity)?
The third line of effort supports technical capability building in laboratories (including training in CBW detection methods) and includes cybersecurity assessments and select upgrades to protect detection processes, documentation, and reporting systems.
Why does the program include cybersecurity components for laboratories?
The program recognizes that laboratory results, methods, and reporting chains are high-value targets for interference, manipulation, or theft. Strong cyber hygiene helps maintain confidence in findings and protects sensitive detection work.
What is the maximum funding amount available per award?
The award ceiling is up to $10,000,000 per award.
How many awards does the agency expect to make?
The agency anticipates making around 10 awards.
What is the CFDA number listed for this opportunity?
The listed CFDA number is 19.033.
What is the funding activity category?
The funding activity category is labeled "Other," reflecting a cross-cutting mix of industry engagement, training, laboratory capability development, and cybersecurity support.
When was this opportunity created?
The opportunity was created on 2025-05-30.
What is the original application closing date?
The original application closing date is 2025-07-30.
Who is eligible to apply?
Eligibility includes U.S. for-profit companies, U.S.-based nonprofits (with or without 501(c)(3) status), and U.S.-based institutions of higher education (public, private, or state). It also allows applications from foreign-based nonprofits/NGOs, Federally Funded Research and Development Centers (FFRDCs), Public International Organizations (PIO), Foreign Public Entities (FPE), and foreign-based institutions of higher education.
Are U.S. nonprofits required to have 501(c)(3) status to apply?
No. U.S.-based nonprofits are eligible with or without 501(c)(3) status.
Are foreign organizations allowed to apply?
Yes. The eligibility list includes foreign-based nonprofits/NGOs, Public International Organizations (PIO), Foreign Public Entities (FPE), and foreign-based institutions of higher education.
Are Federally Funded Research and Development Centers (FFRDCs) eligible?
Yes. FFRDCs are explicitly included in the eligibility list.
What kinds of partners or capabilities does the program aim to bring together?
The opportunity is designed to bring together operational responders, technical laboratories, cybersecurity expertise, and private-sector supply-chain and compliance capacity to reduce both the likelihood and the impact of CBW development or use tied to Russia.
Does the program focus only on response after an incident?
No. The program includes both prevention-oriented work (industry compliance and due diligence to block sensitive procurement) and response-oriented work (first responder training, evidence-preserving sample handling), plus laboratory detection capability and cybersecurity protections.
What does "BBCP industry" refer to in this opportunity?
BBCP refers to the biological, biotechnology, chemical, and pharmaceutical industry.
What does the program mean by "dual-use materials and equipment"?
Within this opportunity, dual-use materials and equipment are items that can have legitimate commercial or research uses but could also be diverted to support CBW-related research, development, production, or weaponization.
What kinds of improvements are envisioned for industry compliance and due diligence?
The opportunity highlights improvements such as stronger customer and end-user screening, better recognition of suspicious procurement attempts, tighter controls over dual-use materials and equipment, and broader adoption of best practices to reduce diversion risk across manufacturing and distribution networks.
What outcomes is the program trying to achieve for laboratories?
The program aims for beneficiary labs to reliably identify relevant agents and indicators of CBW use through training in detection methods, while also improving the cybersecurity of detection processes, documentation, and reporting systems.
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