Opportunity Information: Apply for PAR 19 342

The Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Institutionally-Focused Research Education Award to Promote Diversity (UE5 - Clinical Trial Not Allowed), funding opportunity number PAR-19-342, is an NIH cooperative agreement designed to strengthen the biomedical research workforce by expanding access to high-quality career development support for scientists from diverse backgrounds, including individuals from groups underrepresented in the biomedical and behavioral sciences. It sits within NIH's Research Education Program (UE5), meaning the emphasis is on structured education and career preparation activities rather than supporting a traditional hypothesis-driven research project. As noted in the title, clinical trials are not allowed under this funding mechanism.

The central purpose of this program is to build and deliver coordinated, well-designed education and mentoring experiences that help MOSAIC K99/R00 awardees successfully transition into independent, research-intensive faculty careers and thrive once they get there. In practical terms, the UE5 supports programming that improves readiness for the academic job market and early faculty success, focusing on the skills, professional networks, and mentoring relationships that often determine whether a promising postdoctoral researcher can secure and sustain an independent research trajectory at a research-intensive institution.

The FOA prioritizes two main types of activities. First are Courses for Skills Development, which generally means organized curricula, workshops, institutes, or similar training experiences that teach competencies needed for independence. While the FOA text here does not list every topic, in the MOSAIC context these courses commonly align with the realities of faculty careers: grantsmanship and funding strategies, building and managing a research program, leadership and lab management, scientific communication, publishing strategy, responsible conduct and rigor/reproducibility expectations, networking, negotiation, and other professional skills that directly affect independence and advancement. Second are Mentoring Activities, which can include structured mentoring networks, coaching, committee-based mentoring models, near-peer mentoring, and other intentional approaches that connect K99/R00 scholars with experienced researchers who can provide guidance, feedback, sponsorship, and community as they navigate the transition to faculty roles.

Applications are particularly encouraged from organizations of biomedical researchers such as scientific societies and similar member-based professional organizations. NIH is looking for applicants that can function as a centralized hub for scientific communication and networking in fields aligned with the NIH mission. Competitive applicants are expected to show an established track record of delivering professional development and networking opportunities for the next generation of biomedical researchers, along with a clear and demonstrated commitment to improving diversity in the biomedical research workforce. The logic is that these organizations are often uniquely positioned to convene scholars across institutions, create cross-cutting mentoring networks, and provide field-specific professional development at scale.

From an administrative standpoint, this opportunity is categorized as discretionary funding and uses a cooperative agreement instrument. That typically indicates a more substantial, active partnership with NIH program staff compared with a standard grant, often including coordination, shared expectations around milestones or program elements, and ongoing communication to ensure the supported activities meet program goals and serve the intended participant population effectively.

Eligibility includes several organizational types: nonprofits with 501(c)(3) status (excluding institutions of higher education), nonprofits without 501(c)(3) status (excluding institutions of higher education), for-profit organizations other than small businesses, and small businesses. At the same time, the FOA explicitly restricts foreign involvement: non-U.S. (non-domestic) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed. Applicants therefore need to ensure both the applicant organization and the proposed program activities are structured to comply with NIH's domestic-only requirement for this FOA.

The opportunity is administered by the National Institutes of Health under CFDA number 93.859. The original closing date listed for the opportunity was December 14, 2020. While the listing does not specify an award ceiling or the expected number of awards in the provided source data, the key takeaway is that the program is meant to resource high-impact, scalable education and mentoring models that measurably improve the preparation, transition, and early-career success of MOSAIC K99/R00 scholars as they pursue independent academic careers in biomedical research.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Institutionally-Focused Research Education Award to Promote Diversity (UE5 - Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
  • This funding opportunity was created on 2019-08-14.
  • Applicants must submit their applications by 2020-12-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, For-profit organizations other than small businesses, Small businesses.
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