Opportunity Information: Apply for W81XWH 22 CPMRP TRA
The DOD Chronic Pain Management, Translational Research Award (FY22 CPMRP TRA; Funding Opportunity Number W81XWH 22 CPMRP TRA) is a Department of Defense research funding opportunity run through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA). It is designed specifically to push chronic pain management research past early discovery and into real-world clinical use. The central idea is to fund translational work that takes evidence-based findings and turns them into practical clinical applications, such as healthcare products, patient-facing or clinician-facing technologies, clinical practice guidelines, and models of care that can be implemented in healthcare settings.
A key expectation is that applicants clearly connect their proposed research to how chronic pain is actually managed in practice. Proposals are expected to show, in a concrete and credible way, how the work will inform the development, refinement, or revision of standards of care, clinical recommendations, or practice guidelines for chronic pain management. In other words, this is not simply a mechanism for generating more basic knowledge about pain; it is meant to produce outcomes that can change what clinicians do, what systems implement, or what guidance organizations adopt.
The opportunity also draws a clear boundary around opioid-related work. Projects that seek to advance new or novel opioid-based therapeutic interventions are considered outside the intent of the award and are not intended to be selected for funding. However, studies that fit within current prescribing realities and aim to understand, improve, or reduce opioid utilization in chronic pain management are explicitly allowed. This makes room for pragmatic research on opioid stewardship, prescribing optimization, alternative approaches that decrease opioid reliance, and care pathways that reduce risk while still addressing pain and function.
From an administrative and funding-structure standpoint, the award can be made as either a grant or a cooperative agreement, and it falls under the Science and Technology and other Research and Development category (CFDA 12.420). Eligibility is described as unrestricted, meaning it is open to a wide range of applicant organizations and entity types, subject to any additional eligibility clarifications that may appear in the full announcement. The posting lists an expected number of awards of about two. The notice shows an award ceiling value of 0, which typically indicates the ceiling is not specified in the summary field and that applicants would need to consult the full funding announcement for budget limits, expectations, or negotiation details.
The opportunity was created on May 24, 2022, with an original application closing date of October 13, 2022. Overall, the program message is that DoD is looking for near-term, implementation-oriented chronic pain management research that can credibly lead to deployable tools, improved care models, and guideline-relevant evidence, while avoiding the development of new opioid therapies and instead supporting work that reduces opioid reliance within current clinical practice.Apply for W81XWH 22 CPMRP TRA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Chronic Pain Management, Translational Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on May 24, 2022.
- Applicants must submit their applications by Oct 13, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: DOD Chronic Pain Management, Translational Research Award (FY22 CPMRP TRA)
What is the DOD Chronic Pain Management, Translational Research Award (FY22 CPMRP TRA)?
It is a Department of Defense (DoD) research funding opportunity focused on chronic pain management translational research. The program is designed to move evidence-based chronic pain findings beyond early discovery and into real-world clinical use.
Who runs this funding opportunity?
The opportunity is run through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under the DoD chronic pain management research program.
What is the Funding Opportunity Number?
The Funding Opportunity Number is W81XWH 22 CPMRP TRA.
What is the main purpose of this award?
The central purpose is to fund translational work that turns evidence-based findings into practical clinical applications that can be implemented in healthcare settings. The emphasis is on near-term, implementation-oriented outcomes rather than generating basic knowledge alone.
What does "translational" mean in the context of this opportunity?
In this opportunity, "translational" means taking research findings that already have evidence behind them and advancing them toward products, tools, care models, or guidance that can be used in clinical practice.
What kinds of deliverables or outcomes are encouraged?
The announcement highlights practical clinical applications such as healthcare products, patient-facing or clinician-facing technologies, clinical practice guidelines, and models of care that can be implemented in healthcare settings.
Does the proposed research need to connect to real-world chronic pain management?
Yes. A key expectation is that applicants clearly connect the proposed work to how chronic pain is managed in practice, and explain how the research will translate into changes that matter in clinical settings.
How should applicants address standards of care or clinical guidelines?
Proposals are expected to show, concretely and credibly, how the work will inform the development, refinement, or revision of standards of care, clinical recommendations, or practice guidelines for chronic pain management.
Is this award intended to support basic pain research?
No. The program description draws a distinction between basic knowledge generation and work that produces outcomes that can change clinical practice, healthcare system implementation, or guidance adopted by organizations.
Are opioid-based therapy development projects allowed?
Projects that seek to advance new or novel opioid-based therapeutic interventions are described as outside the intent of the award and are not intended to be selected for funding.
Is any opioid-related research allowed under this opportunity?
Yes. Studies that fit within current prescribing realities and aim to understand, improve, or reduce opioid utilization in chronic pain management are explicitly allowed.
What are examples of opioid-related topics that appear to fit the stated intent?
The description indicates space for pragmatic research on opioid stewardship, prescribing optimization, alternative approaches that decrease opioid reliance, and care pathways that reduce risk while addressing pain and function.
What funding mechanisms may be used for awards?
The award can be made as either a grant or a cooperative agreement.
What is the CFDA number and category listed for this opportunity?
It is listed under CFDA 12.420 and falls within the Science and Technology and other Research and Development category.
Who is eligible to apply?
Eligibility is described as unrestricted, meaning it is open to a wide range of applicant organizations and entity types, subject to any additional eligibility clarifications that may appear in the full announcement.
How many awards are expected?
The posting lists an expected number of awards of about two.
Is there a maximum award amount (award ceiling)?
The notice shows an award ceiling value of 0, which typically means the ceiling is not specified in the summary field. Applicants would need to consult the full funding announcement for budget limits, expectations, or negotiation details.
When was this opportunity created, and what was the original closing date?
The opportunity was created on May 24, 2022, and the original application closing date was October 13, 2022.
What overall types of projects does DoD seem to be looking for through this award?
The program message emphasizes near-term, implementation-oriented chronic pain management research that can credibly lead to deployable tools, improved models of care, and guideline-relevant evidence, while avoiding development of new opioid therapies and supporting work that reduces opioid reliance within current clinical practice.
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| DOD Chronic Pain Management, Clinical Exploration Award Apply for W81XWH 22 CPMRP CEA Funding Number: W81XWH 22 CPMRP CEA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Breast Cancer, Transformative Breast Cancer Consortium Award Apply for W81XWH 22 BCRP TBCCA 2 Funding Number: W81XWH 22 BCRP TBCCA 2 Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Reaching a New Energy Sciences Workforce for High Energy Physics (RENEW-HEP) Apply for DE FOA 0002759 Funding Number: DE FOA 0002759 Agency: Department of Energy - Office of Science, Office of Science Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
| DOD Parkinson's Synergistic Idea Award Apply for W81XWH 22 PRP SIA Funding Number: W81XWH 22 PRP SIA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Parkinson's Investigator-Initiated Research Award Apply for W81XWH 22 PRP IIRA Funding Number: W81XWH 22 PRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Parkinson's Early Investigator Research Award Apply for W81XWH 22 PRP EIRA Funding Number: W81XWH 22 PRP EIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences Apply for 22 600 Funding Number: 22 600 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $1,200,000 |
| “Delivering Scalable Harmful Algal Bloom (HAB) Prevention and Management Technologies for Freshwater Ecosystems for the Ohio River” Apply for W81EWF 22 SOI 0021 Funding Number: W81EWF 22 SOI 0021 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
| NASA Innovative Advanced Concepts (NIAC) Phase I Apply for 80HQTR22NOA01 23NIAC A1 Funding Number: 80HQTR22NOA01 23NIAC A1 Agency: National Aeronautics and Space Administration, NASA Headquarters Category: Science and Technology and other Research and Development Funding Amount: $175,000 |
| DoD Melanoma, Focused Program Award- Rare Melanomas Apply for W81XWH 22 MRP FPA Funding Number: W81XWH 22 MRP FPA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Melanoma, Team Science Award Apply for W81XWH 22 MRP TSA Funding Number: W81XWH 22 MRP TSA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Melanoma, Melanoma Academy Scholar Award Apply for W81XWH 22 MRP MASA Funding Number: W81XWH 22 MRP MASA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Melanoma, Idea Award Apply for W81XWH 22 MRP IA Funding Number: W81XWH 22 MRP IA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Melanoma, Mid-Career Accelerator Award Apply for W81XWH 22 MRP MCAA Funding Number: W81XWH 22 MRP MCAA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Inundated Heritage Data Collection, Community Outreach, and Public Dissemination, Willamette Valley, Oregon Apply for W81EWF 22 SOI 0016 Funding Number: W81EWF 22 SOI 0016 Agency: Department of Defense, Engineer Research and Development Center Category: Science and Technology and other Research and Development Funding Amount: $200,000 |
| “Evaluating the Economic Implications of Low Flow Augmentation on the Ohio River” Apply for W912HZ 22 SOI 0022 Funding Number: W912HZ 22 SOI 0022 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $45,000 |
| “Evaluating the Economic Implications of Low Flow Augmentation on the Ohio River" Apply for W81EWF 22 SOI 0022 Funding Number: W81EWF 22 SOI 0022 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $45,000 |
| Integrated Harmful Algal Bloom (HAB) prediction, prevention, and management strategies for Florida’s St. Lucie Estuary System Apply for W81EWF 22 SOI 0018 Funding Number: W81EWF 22 SOI 0018 Agency: Department of Defense, Engineer Research and Development Center Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
| Delivering Scalable Harmful Algal Bloom (HAB) Prevention Technologies in the Ohio Region Apply for W81EWF 22 SOI 0020 Funding Number: W81EWF 22 SOI 0020 Agency: Department of Defense, Engineer Research and Development Center Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
| Delivering scalable Harmful Algal Bloom (HAB) management technologies in the Ohio region Apply for W81EWF 22 SOI 0019 Funding Number: W81EWF 22 SOI 0019 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
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